November 8, 2023
A research team used Sweden's Total Population Register to identify all 445,790 individuals born in the five years from 1987 through 1991 who remained alive and resident in Sweden during the follow-up period (2001-2014).
The team then consulted the National Patient Register (NPR) to identify the 3,534 members of this cohort who received an ADHD diagnosis before turning eighteen.
Next, they used two national registers (the NPR and the Swedish Prescribed Drug Register) to identify those who also received an ADHD diagnosis or medication prescription in adulthood. They categorized these as "ADHD persisters," as opposed to "ADHD remitters," who did not seek further ADHD-related contact with healthcare services in adulthood.
Using national personal identification numbers, they were also able to link this data to demographic data in the Longitudinal Integration Database for Health Insurance and Labor Market Studies and to cost data in the Cost Per Patient database.
The team adjusted for known confounders. Parental education and family income were used as proxies for socioeconomic status. They also adjusted fr sex and year of birth.
Of the 3,534 individuals who received an ADHD diagnosis in childhood, 62 percent were classified as persisters and 38 percent as remitters in young adulthood.
The mean annual healthcare expenditure for individuals with a childhood ADHD diagnosis was three times higher than for those without such a diagnosis: $1,223 versus $418(after conversion from Swedish króna into U.S. dollars). Broken down further, it was $854 versus $226 for inpatient care, $209 versus $104 for outpatient care, and $158 versus $87 for medication.
Focusing just on the ADHD group, the mean annual healthcare expenditure for those whose ADHD care persisted into young adulthood was 74 percent greater than for remitters:$1,456 versus $837 (which was still twice as high as for no childhood diagnosis). Broken down further, it was $1,014 versus $589 for inpatient care,$246 versus $151 for outpatient care, and $196 versus $96 for medication.
Inpatient care was the main driver of costs in individuals with a childhood ADHD diagnosis. Delving deeper into causes, almost a third of inpatient care was associated with drug or alcohol abuse, 15 percent with injuries, 14 percent with various somatic ailments, and the remainder with comorbid psychiatric disorders(primarily autism, schizophrenia, depression, anxiety).
The authors emphasized that "A novel finding in this study was that individuals with childhood ADHD who no longer had ADHD-related contact with healthcare services in adulthood (remitters) continued to show severe psychiatric and somatic health problems, often leading to hospitalization. This group of individuals showed intermediate profiles on outcomes, with values lower than the ADHD persistent group but higher than the non-ADHD group."
Ebba Du Rietz, Andreas Jangmo, Ralf Kuja-Halkola, Zheng Chang, Brian M. D'Onofrio, EwaAhnemark, Tamara Werner-Kiechle, and Henrik Larsson, "Trajectories of healthcare utilization and costs of psychiatric and somatic multimorbidity in adults with childhood ADHD: a prospective register-based study," Journal of child Psychology and Psychiatry 61:9 (2020), 959-968, https://doi.org/10.1111/jcpp.13206.